![]() ![]() The protection from Rh immune globulin lasts for 12 weeks. How long does Rh immune globulin protect me and my baby? There were no increased rates of bloodborne diseases in a study of women who got Rh immune globulin and those who did not. The manufacturers screen donors for diseases, and the manufacturing process decreases the amount of any infectious virus in the medicine. It is also remotely possible for a virus or disease to be transmitted, though this is unlikely. Let your doctor know about any unusual symptoms right away. That means it is possible to react to it, similar to a blood transfusion reaction. Rh immune globulin is made from donated human blood. Side effects are not common but can include redness, swelling, itching at the injection site, and fever. People who get it usually report it feels like most other shots. The Rh immune globulin injection can be painful but is over quickly. At that time, HDN happened in 10% of pregnancies, leading to infant deaths in 1% of all pregnancies. Before its discovery in the 1960s, there was no way to prevent Rh sensitization. Rh immune globulin tricks your body into thinking that it has already made antibodies so that it does not start the process of making its own.īeing treated with Rh immune globulin is very effective. Rh immune globulin, also known as Rhogam, Rhophylac, and other brand names, is an injection that your nurse can give you. Protecting your baby if you have Rh-negative blood Your body does not tend to mind “seeing” blood with fewer Rh proteins than it is used to seeing, only more. Sensitization does not happen if a mother with Rh-positive blood is exposed to Rh-negative blood. Usually, there will not be complications until a subsequent pregnancy. It takes time for the mother’s body to make enough antibodies to cause problems. However, it can happen with any bleeding during pregnancy. It is most common for the baby’s blood to cross into the mother’s bloodstream during labor and delivery. The antibodies cross the placenta and cause hemolytic disease of the newborn (HDN), which can lead to many serious health problems for the baby, including: Antibodies are proteins that destroy invading substances like viruses, bacteria, and cells. Her body recognizes the baby’s blood as not belonging to her and makes anti-Rh antibodies against it. When a mother with Rh-negative blood carries a baby with Rh-positive blood, the mother becomes sensitized when the blood mixes. Why Rh-negative blood matters in pregnancy It is much more common to have Rh-positive blood. About 15% of people in the United States have Rh-negative blood. If you are Rh-negative, you have a tiny amount of it.Ī handful of people worldwide are Rh-null, meaning they have none of the Rhesus protein at all. If you are Rh-positive, you have a lot of the Rhesus protein. Your genetics determine whether you are Rh negative or positive. Rh stands for Rhesus factor - a protein on the surface of red blood cells. Before the discovery of Rh immune globulin in the 1960s, up to 10% of babies had health problems from sensitization, and 1% died. ![]()
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